Scientific Programme
September 1 - 4, 2024 | Cambridge, UKSunday, 1st September
12:30 – 14:00
Registration
Check-In + set-up Posters
14:00 – 14:15
Welcome and Introduction
Sandip Patel
14:15 – 15:15
Annette Draeger Opening Lecture
Speaker: Annette Dolphin (UCL)
Chair: Sandip Patel (UCL)
15:15 – 16:45
Session 1: Plasma membrane – ER junctions: hubs for local and global calcium signaling
Introduction by Indu Ambukdar (NIH/NIDCR)
15:15 – 15:40
15:40 – 16:05
16:05 – 16:30
16:30 – 16:45
Bjorn Diercks (University Medical Center Hamburg-Eppendorf): Initial Ca2+ microdomains in T cells
Isabella Derler (Johannes Kepler University Linz): Photocrosslinking: a novel tool to study Orai1 channel dynamics
Session discussion
16:45
Coffee / Tea Break
17:15 – 18:45
Session 2: Functional and dysfunctional states of calcium binding proteins
Introduction by Daniele Dell’Orco (University of Verona)
17:15 – 17:40
17:40 – 18:05
18:05 – 18:17
18:17 – 18:29
18:29 – 18:45
Alessandra Astegno (University of Verona): TBA
James Ames (University of California at Davies): Regulation of L-type Calcium Channels by Calmodulin and CaBP1
Short talk selected from abstract submissions
Short talk selected from abstract submissions
Session discussion
18:45 – 21:30
Welcome Reception & Dinner
Monday, 2nd September
8:30 – 9:00
Refreshments
9:00 – 10:30
Session 3: Organelle-cross talk
Introduction by Mohammed Trebak (University of Pittsburgh)
9:00 – 9:25
9:25 – 9:50
9:50 – 10:15
10:15 – 10:30
Jen Liou (UT Southwestern Medical Center): Homeostatic Regulation of PIP2-Ca2+ signaling at ER-PM contact sites
Anna Raffaello (University of Padova): TBA
Session discussion
10:30
Coffee / Tea Break
11:00 – 12:30
Session 4: Calcium signalling in disease
Introduction by Khaled Machaca (Weill Cornell Medicine – Qatar)
11:00 – 11:25
11:25 – 11:50
11:50 – 12:02
12:02 – 12:14
12:14 – 12:30
Greg Monteith (University of Queensland): Pathways to targeting calcium channels for cancer therapy
Mo Trebak (University of Pittsburgh): CRAC channels in metabolic disease
Short talk selected from abstract submissions
Short talk selected from abstract submissions
Session discussion
12:30 – 13:00
Flash Talks 1
Chair: Ana Rossi (University of Cambridge)
13:00 – 14:30
Lunch with Poster Session 1
14:30 – 16:00
Session 5: New calcium imaging technologies
Introduction by Robert Campbell (University of Tokyo)
14:30 – 14:55
14:55 – 15:20
15:20 – 15:32
15:32 – 15:44
15:44 – 16:00
Hod Dana (Case Western Reserve University): Development and application of a high-sensitivity version of the calcium-sensitive activity integrator CaMPARI
Claire Deo (EMBL): Chemigenetic molecular tools for photoacoustic imaging of neural activity
Short talk selected from abstract submissions
Short talk selected from abstract submissions
Session discussion
16:00
Coffee / Tea Break
16:30 – 18:00
Session 6: Advances in NAADP signaling
Introduction by Eugen Brailiou (Temple University)
16:30 – 16:55
16:55 – 17:20
17:20 – 17:45
17:45 – 18:00
Jonathan Marchant (Medical College of Wisconsin): TBA
Jiusheng Yan (University of Texas): Crosstalk between NAADP and PI(3,5)P2 signaling mediated by Lsm12 and two-pore channels
Yongjuan Zhao (CUHK-Shenzhen): Regulatory mechanisms of a calcium signaling enzyme, SARM1
Session discussion
18:00 – 18:30
jECS Session
18:00 – 18:12
18:12 – 18:24
18:24 – 18:30
This session will consist of two speakers selected at the jECS meeting.
Speaker 1 – TBA
Speaker 2 – TBA
Session discussion
19:30
Dinner
Bar & Posters
The college bar is open during and following dinner.
Tuesday, 3rd September
8:30 – 9:00
Refreshments
9:00 – 10:30
Session 7: New discoveries in the structure and function of calcium transport ATPases
Introduction by Agnes Enyedi (Semmelweis University, Hungary)
9:00 – 9:25
9:25 – 9:50
9:50 – 10:15
10:15 – 10:30
Jason Bruce (The University of Manchester): Fuelling PMCA in pancreatic diseases
Elizabeth Cartwright (University of Manchester): The pathophysiological role of PMCAs in heart failure and hypertension
Dirk Montag (Leibniz Institute for Neurobiology): The PMCA – neuroplastin liason is essential for hearing and associative learning and memory
Session discussion
10:30
Coffee / Tea Break
11:00 – 12:30
Session 8: The role of allostery in calcium signalling
Introduction by David Weber (University of Maryland)
11:00 – 11:25
11:25 – 11:50
11:50 – 12:02
12:02 – 12:16
12:16 – 12:30
Gary Shaw (University of Western Ontario): Coupling of Binding Sites in S100 Proteins
Ruth Nussinov (National Cancer Institute, Maryland): TBA
Short talk selected from abstract submissions
Short talk selected from abstract submissions
Session discussion
12:30 – 16:30
Free Time
16:30 – 17:30
General Assembley
17:30 – 18:30
Claude Klee Lecture
Speaker: Martha Cyert (Stanford, USA): Discovering new mechanisms for calcineurin signaling
Chair: Jim Putney
19:30
BBQ
Bar & Posters
The BBQ takes place in the college gardens. The college bar is open during and following dinner.
Wednesday, 4th September
8:30 – 9:00
Refreshments
9:00 – 10:30
Session 9: Artificial intelligence
Introduction by Jonathan Marchant (Medical College of Wisconsin)
9:00 – 9:25
9:25 – 9:50
9:50 – 10:02
10:02 – 10:16
10:16 – 10:30
Andreas Bender (University of Cambridge): Artificial Intelligence in Chemical and Biology and Drug Discovery – Methods, Applications, and Pitfalls
Lukas Friedrich (Merck Healthcare KGaA): TBA
Short talk selected from abstract submissions
Short talk selected from abstract submissions
Session discussion
10:30
Coffee / Tea Break
11:00 – 12:30
Session 10: Annexins and the S100 proteins
by Ursula Rescher (University of Münster)
11:00 – 11:25
11:25 – 11:50
11:50 – 12:02
12:02 – 12:16
12:16 – 12:30
Axel Brakhage (Leibniz Institute for Natural Product Research and Infection Biology): Pathogenic fungus hijacks human S100A10 (p11) to redirect fungal-containing phagosomes to non-degradative pathway
Short talk selected from abstract submissions
Short talk selected from abstract submissions
Session discussion
12:30 – 13:00
Flash Talks 2
Chair: Martin Bootman (The Open University)
13:00 – 14:30
Lunch with Poster Session 2
14:30 – 16:00
Session 11: Calcium signaling at membrane contact sites
introduced by Nicolas Demaurex (Univeristy of Geneva)
14:30 – 14:55
14:55 – 15:20
15:20 – 15:45
15:45 – 16:00
Jennifer Rieusset (Claude Bernard University Lyon): Role of endoplasmic reticulum-mitochondria calcium coupling in metabolic health and disease
Raz Palty (Israel Institute of Technology): TBA
Alex van Vliet (MRC Laboratory of Molecular Biology in Cambridge): Autophagy Initiation through (rapid) membrane contact sites
Session discussion
16:00
Coffee / Tea Break
16:30 – 17:30
Late Breaking Session
Chair: Geert Bultynck (KU Leuven)
Speakers will be announced later
17:30 – 18:30
Sir Michael Berridge Lecture
Speaker: Gaiti Hasan (NCBS, India): Integration of neuromodulatory inputs by intracellular Ca2+ signaling for systemic growth and behaviour
Chair: Andreas Guse
18:30
Concluding Remarks and Awards
by the local organising committee
19:30
Gala Dinner
The gala dinner takes place in the new dining hall. The college bar is open following dinner.
Sponsors
Thank you to our sponsors for making this event a success.
